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Here we discuss our approach to the adult with unexpected thrombocytopenia. This approach can be used by the primary care physician and the consulting hematologist. Separate topics discuss thrombocytopenia in other populations: Neonates – (See "Neonatal thrombocytopenia: Clinical manifestations, evaluation, and …

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Mar 19, 2024 · Acute pancreatitis is an acute inflammatory process of the pancreas. Overall mortality rates in acute pancreatitis are approximately 2 percent, but can be as high as 30 percent in patients with persistent organ failure (severe acute pancreatitis) [ 1 ]. This topic reviews the management of acute pancreatitis. The four essential components of asthma management are patient education, minimizing exposure to asthma triggers, monitoring for changes in symptoms or lung function, and pharmacologic therapy. This overview topic presents the goals and components of asthma management. It is applicable to both children and adults.Vaginitis is the general term for disorders of the vagina caused by infection, inflammation, or changes in the normal vaginal flora. Symptoms include abnormal vaginal discharge, odor, pruritus, and/or discomfort. The initial evaluation typically consists of a history, physical examination, and tests for specific infections, including sexually ...Oct 25, 2023 ... Outline · - Discontinuing hypertonic saline used as initial therapy · - Fluid restriction · - Other therapies for chronic hyponatremia ·...

Apr 5, 2024 · INTRODUCTION. —. Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. The clinical presentation of CAP varies, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis.

For individuals with skin abscess, we suggest initial treatment with parenteral antibiotics in the following circumstances: Systemic signs of toxicity (eg, fever >100.5°F/38°C, hypotension, sustained tachycardia) Rapid progression of erythema or abscess. Extensive abscess or surrounding erythema.

About UpToDate UpToDate is the evidence-based, point-of-care resource trusted for reliable clinical answers around the world. UpToDate incorporates the latest medical findings, the best available evidence, and practical recommendations for patient care — so whatever your clinical question, you can be sure to find the answers you need.Oct 25, 2023 · A table summarizing the emergency management of acute hyponatremia in adults is provided ( table 1 ). An alternative approach, recommended in by European organizations, is to treat with two 150 mL bolus infusions of 3 percent saline, each given over 20 minutes, measuring the serum sodium between infusions [ 28 ]. Learn how to address excessive tardiness and find some of the simplest solutions to tardiness in the workplace. Human Resources | How To WRITTEN BY: Charlette Beasley Published Nov...In February 2020, the World Health Organization (WHO) designated the disease COVID-19, which stands for coronavirus disease 2019 [ 1 ]. The WHO declared an end to the COVID-19 global health emergency in May 2023, more than three years after its emergence. This topic will discuss the virology, epidemiology, and prevention of COVID-19.

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Jan 25, 2023 · The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the imidazoles (ketoconazole). An overview of the use of azole agents for the treatment of various systemic fungal infections will be reviewed here.

Acute pulmonary embolism (PE) is a common and sometimes fatal disease with a variable clinical presentation. It is critical that therapy be administered in a timely fashion [ 1-5 ]. The treatment, prognosis, and follow-up of patients with acute PE are reviewed here. The epidemiology, pathophysiology, clinical presentation, and diagnosis …Although hypokalemia can be transiently induced by the entry of potassium into the cells, most cases result from unreplenished gastrointestinal or urinary losses due, for example, to vomiting, diarrhea, or diuretic therapy [ 1-3 ]. (See "Causes of hypokalemia in adults" .) Potassium replacement is primarily indicated when hypokalemia is due to ...If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If not, please enter your Username. Close Subscribe. Subscribe. UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care. About Us ...CLINICAL MANIFESTATIONS. Major clinical features and organ involvement. Constitutional symptoms — Constitutional symptoms such as fatigue, fever, and weight loss are present in most patients with systemic lupus erythematosus (SLE) at some point during the course of the disease.The inpatient management of syndromes associated with moderate and severe alcohol withdrawal is reviewed here. The ambulatory management of mild alcohol withdrawal, the initial diagnosis and treatment of alcohol use disorder, and specific conditions due to alcohol-related organ damage (eg, cirrhosis, pancreatitis) are …Hypoglycemia is the most common acute complication of glucose-lowering therapy and is associated with poor outcomes and quality of life in people with type 1 and type 2 diabetes. Hypoglycemia is more common among patients with type 1 diabetes than those with type 2 diabetes and is usually limited to patients with type 2 diabetes treated …

UpToDate is an online platform that offers evidence-based clinical information and decision support for health care professionals and patients. To use UpToDate, you need to …Cirrhosis represents a late stage of progressive hepatic fibrosis characterized by distortion of the hepatic architecture and the formation of regenerative nodules. It is generally considered to be irreversible in its advanced stages, at which point the only option may be liver transplantation. In earlier stages, specific treatments aimed …PARENTERAL DRUGS. A variety of parenteral and oral antihypertensive drugs are available for use in these patients ( table 1) [ 1-7 ]. Few studies have compared these agents with one another, and all are tolerated reasonably well [ 8,9 ]. Thus, the drug of choice is often dictated by the type of hypertensive emergency and the local hospital ...To encourage domestic travel, Thailand is partnering with Tinder to offer trips designed for singles around Thailand. Trips are scheduled in December 2020 and January 2021. With in...Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical radiographic syndrome of heterogeneous etiologies that are grouped together because of similar findings on neuroimaging studies. It is also often referred to as: To continue reading this article, you must sign in with your personal, hospital, or group practice subscription ...

Acute pancreatitis should be suspected in patients with severe acute upper abdominal pain but requires biochemical or radiologic evidence to establish the diagnosis. This topic will review the clinical manifestations and diagnosis of acute pancreatitis. The etiology, pathogenesis, assessment of severity, and management of acute pancreatitis …

Colorectal cancer (CRC) is a common and lethal disease. In the United States, approximately 153,000 new cases of large bowel cancer are diagnosed annually [ 1 ]. CRC can be diagnosed after the onset of symptoms or through screening asymptomatic individuals. The clinical presentation, diagnosis, and staging of CRC will be reviewed here.Although hypokalemia can be transiently induced by the entry of potassium into the cells, most cases result from unreplenished gastrointestinal or urinary losses due, for example, to vomiting, diarrhea, or diuretic therapy [ 1-3 ]. (See "Causes of hypokalemia in adults" .) Potassium replacement is primarily indicated when hypokalemia is due to ...Blood pressure is reported as the systolic pressure over diastolic pressure (eg, 120/70 or "120 over 70"). Untreated high blood pressure increases the strain on the heart and arteries, eventually causing organ damage. High blood pressure increases the risk of heart failure, heart attack (myocardial infarction), stroke, and kidney failure.Acute pancreatitis should be suspected in patients with severe acute upper abdominal pain but requires biochemical or radiologic evidence to establish the diagnosis. This topic will review the clinical manifestations and diagnosis of acute pancreatitis. The etiology, pathogenesis, assessment of severity, and management of acute pancreatitis …Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating motor weakness involving ocular, bulbar, limb, and/or respiratory muscles. The weakness is due to an antibody-mediated, immunologic attack directed at proteins in the postsynaptic membrane of the neuromuscular junction (acetylcholine receptors or ...Mar 28, 2024 · Choice of initial therapy in most patients — The three primary options for antihypertensive drug therapy in most patients include an ACE inhibitor (or ARB), a calcium channel blocker, or a thiazide diuretic (preferably a thiazide-like diuretic) [ 3 ]. Mar 28, 2024 ... Outline · Suboptimal response · - Adjunctive CBT · - Pharmacologic management · No response to SRI treatment · Partial response ...Intrauterine tamponade (with a balloon, packing, or vacuum) may be used to manage patients with postpartum hemorrhage (PPH) resulting from uterine atony that is not controlled by uterotonic medications and uterine massage. However, outcome data regarding vacuum-induced tamponade are limited.

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To encourage domestic travel, Thailand is partnering with Tinder to offer trips designed for singles around Thailand. Trips are scheduled in December 2020 and January 2021. With in...

What's New. Our editors select a small number of the most important updates and share them with you via What's New. See these updates by clicking on the specialty you are interested in below. You may also enter "What's new" in the search box. Find Out What's New In:Oct 31, 2023 · Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF. Measures to cut down on leveraged crypto trades could entice institutional buyers and make bitcoin more useful as a currency. In an effort to curb cryptocurrency speculation, finan...INTRODUCTION. Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy (TMA) caused by severely reduced activity of the von Willebrand factor-cleaving protease ADAMTS13. It is characterized by small-vessel platelet-rich thrombi that cause thrombocytopenia, microangiopathic hemolytic anemia, and …The clinical features of KD reflect widespread inflammation of primarily medium-sized muscular arteries. Diagnosis is based upon evidence of systemic inflammation (eg, fever) in association with signs of mucocutaneous inflammation. The characteristic bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, rash, extremity ...Mar 19, 2024 · Acute pancreatitis is an acute inflammatory process of the pancreas. Overall mortality rates in acute pancreatitis are approximately 2 percent, but can be as high as 30 percent in patients with persistent organ failure (severe acute pancreatitis) [ 1 ]. This topic reviews the management of acute pancreatitis. Gastroesophageal reflux becomes a disease when it either causes macroscopic damage to the esophagus or causes symptoms. This topic will review the initial management of gastroesophageal reflux disease (GERD) and management of patients with recurrent GERD when treatment is discontinued. Our recommendations are largely …Get the clinical information you need with a personal subscription to UpToDate. Trusted for more than 30 years, UpToDate® is the clinical decision support resource that provides …

In February 2020, the World Health Organization (WHO) designated the disease COVID-19, which stands for coronavirus disease 2019 [ 1 ]. The WHO declared an end to the COVID-19 global health emergency in May 2023, more than three years after its emergence. This topic will discuss the virology, epidemiology, and prevention of COVID-19.Learn how to address excessive tardiness and find some of the simplest solutions to tardiness in the workplace. Human Resources | How To WRITTEN BY: Charlette Beasley Published Nov...Display complete list of interactions for an individual item by clicking item name. Add another item to analyze for potential interactions. NOTE: This tool does not address chemical compatibility related to I.V. drug preparation or administration. View interaction detail by clicking on link (s) below.UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, …Instagram:https://instagram. roblox free playing Intravenous thrombolysis can be administered up to 4.5 hours after symptom onset, and mechanical thrombectomy can be administered up to 24 hours after symptom onset. (See "Approach to reperfusion therapy for acute ischemic stroke" and "Intravenous thrombolytic therapy for acute ischemic stroke: Therapeutic use" and "Mechanical …UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, … richmond flights The use of any anticoagulant is associated with an increased risk of bleeding, and bleeding complications can be life-threatening. Management of bleeding in individuals who are receiving a direct oral anticoagulant (DOAC) can be challenging because routine coagulation tests cannot generally be used to determine the degree of …INTRODUCTION. Appendicitis, an inflammation of the vestigial vermiform appendix, is one of the most common causes of the acute abdomen and one of the most frequent indications for an emergency abdominal surgical procedure worldwide [ 1,2 ]. The clinical manifestations and differential diagnosis of appendicitis in adults will be reviewed here. sun wing For individuals and groups up to 19. Medical practices and other groups can place their UpToDate subscription orders together online, pay for them in a single transaction, and receive all the benefits of a personal subscription. Subscribe or view pricing for your group by selecting the “Purchase for Others” option. Subscribe Or See Pricing.Patient Education. UpToDate offers two levels of content for patients: The Basics are short overviews. They are written in accordance with plain language principles and answer the four or five most important questions a person might have about a medical problem. Beyond the Basics are longer, more detailed reviews. how to reboot android phone Mar 15, 2023 · Vaginal yeast infections (also called yeast vaginitis or vaginal candidiasis) are a common problem in women. The most common symptoms are itching and irritation of the vulva and around the opening of the vagina. Vaginal yeast infections usually occur as infrequent episodes, but can recur frequently and may cause chronic persistent symptoms. Oct 25, 2023 · A table summarizing the emergency management of acute hyponatremia in adults is provided ( table 1 ). An alternative approach, recommended in by European organizations, is to treat with two 150 mL bolus infusions of 3 percent saline, each given over 20 minutes, measuring the serum sodium between infusions [ 28 ]. rent pool near me Once the diagnosis of either UA or an acute NSTEMI is made, the acute management of the patient involves the simultaneous achievement of several goals: Relief of ischemic pain. (See 'Initial medical therapy' below.) Assessment of the patient's hemodynamic status and correction of abnormalities. Hypertension and tachycardia, both … james earl jones reads the bible Art, as we all know, is about following a set number of rules handed to you by another person. In the latest New York Magazine cover story, art critic Jerry Saltz lists 33 steps to... ga tech game Other manifestations include lower abdominal pain and cramping, low-grade fever, nausea, and anorexia [ 2,5 ]. Diarrhea may be associated with mucus or occult blood, but melena or hematochezia are rare. Fever is associated with CDI in about 15 percent of cases; temperature >38.5°C may occur in the setting of nonsevere or severe CDI.Smoking cessation is associated with clear health benefits. Cigarette smoking is the leading preventable cause of death in the United States and worldwide. Tobacco use increases the risk of many acute and chronic diseases, including cancers at many sites. Medications, including nicotine replacement, varenicline, and bupropion, have demonstrated ...Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine Nadia Hansel, MD, MPH, is the interim director of the Department of Medicine in th... chick f la Group A Streptococcus (GAS), or Streptococcus pyogenes, is the leading bacterial cause of tonsillopharyngitis in adults and children worldwide. GAS is one of the few causes of tonsillopharyngitis or pharyngitis for which antibiotic treatment is recommended. The treatment and prevention of group A streptococcal tonsillopharyngitis is reviewed here. flights to qatar Jan 25, 2023 · The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and the imidazoles (ketoconazole). An overview of the use of azole agents for the treatment of various systemic fungal infections will be reviewed here. flights to ontario canada PARENTERAL DRUGS. A variety of parenteral and oral antihypertensive drugs are available for use in these patients ( table 1) [ 1-7 ]. Few studies have compared these agents with one another, and all are tolerated reasonably well [ 8,9 ]. Thus, the drug of choice is often dictated by the type of hypertensive emergency and the local hospital ...Apr 5, 2024 · INTRODUCTION. —. Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. The clinical presentation of CAP varies, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis. how to send a text from email Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine Dr. Mary Catherine Beach, professor in the Division of General Internal Medicine, ...The global prevalence of hypertension is high, and among nonpregnant adults in the United States, treatment of hypertension is the most common reason for office visits and for the use of chronic prescription medications [ 1-3 ]. In addition, roughly one-half of hypertensive individuals do not have adequate blood pressure control.